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Transverse myelitis syndrome may arise from a direct infection or an autoimmune phenomenon after viral infection. Varicella zoster virus infection, a treatable disease, may manifest as chickenpox during primary infection or as herpes zoster due to reactivation. Nowadays, most chickenpox cases occur in immunocompromised patients or unvaccinated persons. Neurological complication with chickenpox is rare and commonly occurs in children. We report here an unusual case of severe myelitis due to chickenpox in an immunocompetent host.